Triphala and BP

By whitepeony44 in 1 Feb 2026 | 19:44
whitepeony44

whitepeony44

 Student
Posts: 11
Member since: 14 Jul 2024
Hi David, I am wondering if it is possible for someone taking 25mg metoprolol QD (at bedtime) to also take a prebiotic fiber supplement containing 220mg Triphala? I understand Triphala can lower BP and heart rate, as well as interfere with CYP450. I am seeking guidance as to whether or not this fiber supplement could be taken safely by this individual. If it is an option, what would be the best time of day to take the supplement? Appreciate your input, Valerie
1 Feb 2026 | 19:44
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Karla Parker

Karla Parker

 Instructor
Posts: 213
Member since: 16 Dec 2024
David said: Triphala does not significantly lower blood pressure or heart rate, in one animal study it did have an effect on CYP1A and CYP3A, but not CYP2D6 which is the pathway that metoprolol is metabolized through. To allay any concerns take the Triphala at breakfast and lunch, and not at dinner.
3 Feb 2026 | 17:30
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whitepeony44

whitepeony44

 Student
Posts: 11
Member since: 14 Jul 2024
Thank you so much. That makes sense. Appreciate it! Valerie
8 Feb 2026 | 21:23
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